Wells Fargo's decision to move its headquarters in San Francisco is the latest sign of how the banking industry is becoming ...

SAN FRANCISCO (AP) — A photojournalist who captured one of the most enduring images of World War II — the U.S. Marines ...

The Niners face an uphill battle to feature in the postseason but a Thursday Night Football win over the Rams will keep their ...

Let's break down two key matchups for the San Francisco 49ers in a pivotal Week 15 Thursday Night Football brawl against the ...

Safeway follows Whole Foods, Macy's, Sephora, Nordstrom, Adidas, and others in closing at least one store or moving out entirely.

San Francisco is on track to have the lowest homicide rate in 60 years, according to the police department and mayor's office ...

San Francisco's Mayor-elect Daniel Lurie plans to restructure the Office of the Mayor to improve efficiency, introducing four policy chiefs to oversee major sectors.

The San Francisco 49ers finally got some good injury news. Linebacker Dre Greenlaw is on track to make his return Thursday ...

The San Francisco Standard, that city’s lively and well-funded digital upstart, is experimenting with tiered membership.

Mission Local curated a list of places where readers can volunteer this holidays. Check it out and let us know of any other ...

Football? Los Angeles Rams vs San Francisco 49ers NFL Week 15 TV channel, how to watch on television, how to stream today.

President-elect Donald Trump announced Monday he will nominate Bay Area attorney Harmeet Dhillon for a position at the U.S.