The 28-year-old took to social media on Wednesday to share a heartfelt message for 49ers fans after his injury-plagued ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Having suffered a knee injury that landed him on injured reserve during a snowy loss to the Bills on Sunday night, 49ers ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

San Francisco 49ers running back Christian McCaffrey has spoken out after being placed on injured reserve with yet another ...

Givens suffered a torn pec in the 49ers’ Week 13 loss to the Buffalo Bills. His injury-riddled season is over after only ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

The San Francisco 49ers are not in a good place right now, and that includes the status of Christian McCaffrey. The All-Pro ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...