Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics. Generation of a stable, high-performance, monoclonal cell line producing a ...

It leverages its biocompatibility, degradability, and cationic properties to form complexes with plasmid DNA. By preparing suitable ... biological signaling molecules, including recombinant proteins, ...

A recombinant reporter virus (rSVA ... cells were transfected with a control plasmid or plasmids expressing RIG-I, MDA5, MOV10, ZCCHC3, DDX46, and Serinc5 (2 μg per well) using X-tremeGENE HP DNA ...

Both genes were codon-optimized and cloned into the pJL1 plasmid, with McbA featuring an N-terminal CAT-Strep-Linker fusion (CSL-tag) for purification. The DNA library was generated ... with 50 µg/mL ...

The FDA has authorized an expanded access program that will allow for the use of a recombinant bacillus Calmette-Guerin product.

CFO Beth Jantzen reported total revenues of $1.2 million for Q1 2025, a year-over-year increase driven by higher product revenue from DNA Tagging and increased isotopic testing services. Operating ...

You have full access to this article via your institution. This intrinsic property of AAV to undergo intermolecular concatamerization had shown great potential for expanding the current packaging ...

In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

However, the study provides limited new insights into the relationship between retinal lamination defects and overall retinal function. Neural lamination is a common feature of the central nervous ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...