The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities to show what he can do as a runner.

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball. While they are only two games out of first place in the NFC West, they don't look like a playoff team.

The San Francisco 49ers’ playoff chances aren’t completely erased, but they’re low enough that looking toward next year’s offseason and NFL draft aren’t unreasonable. If the 49ers win a couple of games down the stretch and put themselves squarely back in the playoff picture,

While a sense of gratitude is well and nice we also have some thoughts on teams that are failing in epic ways and have to hold them accountable for doing so. Basically, we have a lot of opinions about a lot of things and need to get them out somewhere.

Has the sun officially set on the 49ers? Let's look closer at San Francisco's lost season, Arthur Smith's rising offense in Pittsburgh and big Week 13 trends.

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason games, could return kicks for the Niners as he took a kickoff back 93 yards in the 49ers' preseason finale.

When it comes to quarterbacks, Kyle Shanahan is extremely picky. He often isn't wild about young quarterbacks who have lots of hype. And when he

Holmgren coached at three Bay Area high schools and San Francisco State before climbing to the NFL ranks, where he won two Super Bowls as a 49ers assistant and another as the coach of the Packers.

East Rutherford, NJ — November 24, 2024 — Malik Nabers of the Giants on the bench late in the fourth quarter as the Tampa Bay Buccaneers came to MetLife Stadium and defeated the New York Giants 30-7. Chris Pedota, NorthJersey.com / USA TODAY NETWORK via Imagn Images

The 49ers' disappointing season took another negative turn in their Week 13 loss to the Bills, and George Kittle addressed the injuries.

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and San Francisco 49ers.