The FDA IND approval of UC101 further showcases VectorBuilder’s mature platform of lentiviral manufacturing. In addition to its extensive FDA IND experience with transfection-based lentiviral ...
Lentivirus-mediated transfection was employed to overexpress and knockdown METTL3 in HEI-OC1 cells. Knockdown of METTL3 resulted in increased reactive oxygen species (ROS) levels and apoptosis induced ...
However, lentivirus vector generally do not express the accessory ... When VSV-G-bearing HIV-1 vector is constructed by transient transfection, its transduction titers are generally much higher than ...
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