Should Guerendo start as expected on Sunday, it will be just his second start as a running back since he was in the fourth ...

Kyle Shanahan explains why 49ers rookie Isaac Guerendo is ready to be the starter with Christian McCaffrey and Jordan Mason ...

The 49ers' quarterback room simply isn't good enough. Last season, they had Brock Purdy AND Sam Darnold. That was a good ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

San Francisco 49ers running back Christian McCaffrey reflected on his 2024 NFL season that fell short of expectations with a ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

See who's in and who's out for the Week 14 matchup between the San Francisco 49ers and Chicago Bears on December 8, 2024.

Former 49ers kicker Robbie Gould announced Tuesday that he is leaving the high school head coaching job he took one year ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...