The 49ers opened the practice window for safety Talanoa Hufanga, who has missed the last seven games with a wrist injury.

Kendrick Lamar and SZA announced the Grand National Tour, which will hit 19 stadiums across North America next spring and ...

Heartbreak has struck the 49ers family again with the news that the newborn son of left tackle Trent Williams died on Nov. 24 ...

The Buffalo Bills (9-2) will try to build on a six-game winning streak when they host the San Francisco 49ers (5-6) on Sunday ...

In honor of World Aids Day, San Franciscans came together at the National AIDS Memorial Grove in San Francisco on Saturday ...

Police have arrested a suspect in the murder of an Maxwell George Maltzman, 18, bringing to the forefront an unsolved San ...

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

Wells Fargo is exploring the sale of the San Francisco building where its headquarters are located, a source familiar with ...

The San Francisco Standard, that city’s lively and well-funded digital upstart, is experimenting with tiered membership.

The San Francisco Giants may not have success when it comes to signing free-agent hitters, but their track record with ...

The East Brother Light Station housed on an island in San Francisco Bay is seeking applicants for new inn keepers. The light ...

The meeting is in collaboration with Resilient Los Altos and will be held from at 6 p.m. Wednesday at the Garden House, 400 University Ave., police said in a press release. Police will also review ...