The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

San Francisco 49ers running back Christian McCaffrey reflected on his 2024 NFL season that fell short of expectations with a ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

The 49ers' quarterback room simply isn't good enough. Last season, they had Brock Purdy AND Sam Darnold. That was a good ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

The San Francisco 49ers could say goodbye to RB Jordan Mason, one of their most productive offensive players, in the near ...

There have only been eight trades involving NFL head coaches, but perhaps it’s time for a ninth. As the Chicago Bears begin ...

Josh Allen and the Buffalo Bills put on a show in the snow during "Sunday Night Football" in Week 13, besting the San ...