IF enhances the production of IPA from intestinal Clostridium sporogenes, which directly attenuates platelet activation and thrombosis, and alleviates microvascular thrombosis after I/R injury by ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread ...

However, platelet reactivity to clopidogrel is variable and stent thrombosis can occur suddenly and unexpectedly in up to 3% of patients. Is responsiveness to clopidogrel an indicator of risk of ...

Dr. Woulfe's research interests focus primarily on the intracellular signaling mechanisms of platelet activation and how signaling in platelets contributes to thrombosis in vivo. Agonists that extend ...

A variety of cellular components in addition to platelets contribute to the development and progression of arterial thrombosis, including endothelial cells, leukocytes and erythrocytes ...

It is characterized by the formation of blood clots (thrombosis) and thrombocytopenia, or low platelet counts. Thrombosis: Blood clots, or clumps, can occur in arteries or veins. They have the ...

Could fasting be the key to a healthier heart? Study: Intermittent fasting inhibits platelet activation and thrombosis through the intestinal metabolite indole-3-propionate. Image Credit ...

It has been previously shown that the nuclear receptor subfamily 4 group A (NR4A) plays an important role in cardiovascular ...

Together, both can act synergistically to reduce platelet aggregation and lower thrombosis risk, important factors in the treatment of vascular and cardiovascular disease. This can potentially ...

Until recently, researchers believed that platelet spreading and clot contraction were controlled by the same pathway. However a recent study from Thomas Jefferson University researchers challenges ...