The following is a summary of “A Novel Molecular Regulatory Network in Bone Marrow Mesenchymal Stem Cells for Age-Related Osteoporosis,” published in the March 2025 issue of Clinical Endocrinology by ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

Nature Cell Co. Ltd. won U.S. FDA breakthrough therapy designation of its autologous adipose-derived mesenchymal stem cell therapy, Jointstem, March 20, becoming the first Korean company to earn the ...

The pluripotent and multipotent stem cells are found in the bone marrow, which can differentiate into any tissue in the body.

Concept: Mesenchymal cells exhibit increased chromatin accessibility that leads to catastrophic cell division. Impact: Eliminating cells that display mesenchymal plasticity may slow the progression of ...

In the experiment, cells from the dental pulp of mice were exposed to a cytokine called tumor necrosis factor alpha (TNF-α), which is involved in various inflammatory and autoimmune processes. They ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, P. R. China National Engineering Research Center for Tissue ...

Surgeons restored corneal surfaces in the injured eyes of 14 patients in a small clinical trial. Stem cells from each patient’s healthy eye were cultivated in a lab to grow healthy tissue that could ...

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), especially, exosomes are considered to have diverse therapeutic effects for various significant diseases. MSC-derived exosomes (MSCex) ...