San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

San Francisco 49ers linebacker Fred Warner recently revealed that he has been playing through a bone fracture in his ankle, ...

On Tuesday morning's PFT Live, I threw out the idea of the Bears ditching the normal approach to hiring head coaches and calling the 49ers to see whether they'd be willing to trade Kyle Shanahan.

San Francisco 49ers DB Deommodore Lenoir is showcasing his support for athletes with Down syndrome through custom-designed ...

Should Guerendo start as expected on Sunday, it will be just his second start as a running back since he was in the fourth grade.

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Join Packers Head Coach Matt LaFleur and analyst Larry McCarren as they recap the Packers' Week 13 win over Miami and preview the Week 14 divisional game against the Lions. This week's guest is Isaiah ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Christian McCaffrey practiced little and played less this season, seeing action in four games with 65 touches. He is out for the season with his knee injury that will require a six-week recovery.

McCaffrey was initially said to be out at least six weeks — with five weeks left in the season. Niners head coach Kyle ...

The 49ers' quarterback room simply isn't good enough. Last season, they had Brock Purdy AND Sam Darnold. That was a good ...