Running back Christian McCaffrey has a PCL injury in his right knee and it's a six-week recovery, 49ers coach Kyle Shanahan announced Monday. McCaffrey will be placed on injured reserve, which will likely end his season.

With its 35-10 loss at Buffalo on Sunday night, the 49ers have now dropped three straight to sink to 5-7 on the season. The blowout loss also marked the first time since 2015 and just the fourth time in franchise history that San Francisco has lost back-to-back games by 25 points or more.

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the rest of the regular season.

Patrick Everson breaks down the football weekend that was, including how the 49ers' struggles impacted the books, and some mixed reactions after UM stunned Ohio State.

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and San Francisco 49ers.

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

Sunday after the 49ers lost their seventh game, I asked Brock Purdy to make of the terrible season the 49ers are having. Here's what he said. ME: How do you wra

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, 2024 and Monday with more big watch and wager action. SNF 49ers-Bills and MNF Browns-Broncos stats,

Buffalo Bills quarterback Josh Allen and wide receiver Amari Cooper broke down the unbelievable touchdown they combined for in Week 13.

The San Francisco WAG All-Star has fun and looks good in the snow on Sunday night, but she’s ready to burn her creation.