gut.bmj1d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj7d
Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study
Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic ...
gut.bmj10d
Accuracy of histopathology evaluation in diminutive colonic polyps diagnosed as neoplastic by computer-aided characterisation
The removal of colorectal polyps followed by histological evaluation is the current standard of care. Intracolonoscopy ...
gut.bmj8d
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus
Background Patients with type 2 diabetes mellitus (T2DM) have higher pancreatic cancer (PC) risk. While aspirin has chemopreventive effects on digestive cancers, its effect on PC among patients with ...
gut.bmj13d
Mutational signatures define immune and Wnt-associated subtypes of ampullary carcinoma
Background and objective Ampullary carcinoma (AMPAC) taxonomy is based on morphology and immunohistochemistry. This classification lacks prognostic reliability and unique genetic associations. We ...
gut.bmj3d
Endoscopic full-thickness plication for the treatment of PPI-dependent GERD: results from a randomised, sham controlled trial
Background The majority of endoscopic antireflux procedures for GERD are cumbersome to use and randomised long-term data are sparse. We conducted such a trial to determine the efficacy and safety of a ...
gut.bmj4d
Functional GI disorders: from animal models to drug development
UCLA Center for Neurovisceral Sciences & Women’s Health, Departments of Medicine, Physiology and Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA UCLA Center for Neurovisceral ...
gut.bmj4d
Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications for treatment
Dr V V Smith, Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. Three infants, who presented with intestinal obstruction due to ...
gut.bmj5d
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise ...
gut.bmj2d
Influence of hepatitis delta virus infection on morbidity and mortality in compensated cirrhosis type B
Dr G Fattovich, Servizio Autonomo Clinicizzato di Gastroenterologia, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Università di Verona, Via delle Menegone 10, 37134 Verona, Italy ...
gut.bmj7d
Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis
Background and aims Acute-on-chronic liver failure (ACLF) is characterised by acute decompensation of cirrhosis associated with organ failures. We systematically evaluated the geographical variations ...
gut.bmj3d
Increased expression of IL-16 in inflammatory bowel disease
a Ist Department of Medicine, Christian-Albrechts- University Kiel, Germany, b Institute of Anatomy, Christian-Albrechts- University Kiel, Germany Dr D Seegert, Ist Department of Medicine, ...