Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...

Researchers from the Max Planck Institute of Biochemistry have discovered the mechanism behind an important step in the life ...

A new combination of microscopy methods has revealed exquisite detail of the virus assembly process used by herpes simplex virus during replication.

Infections with the hepatitis E virus often go unnoticed because they cause no symptoms. However, in patients with a weakened ...

Using the vertical β-barrel major capsid proteins and ATPases related to known viral genome-packaging ATPases as examples, we can now re-evaluate the classification of viruses and virus-like ...

Local Rule-Based Theory of Virus Shell Assembly. Proceedings of the National Academy of Sciences of the United States of America, 1994. 91(16): p. 7732-7736. Elrad, O. M. and M.F. Hagan, Mechanisms of ...

Toroidal vortices, common in fluid dynamics, are newly explored in electromagnetism as two distinct forms: vector toroidal ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings ...

The dengue virus has a roughly spherical structure. It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell ...

Researchers reveal new insights into the how the matrix layer of HIV-1 becomes matureResearchers from the Max Planck Institute of Biochemistry have ...

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life ...

The virus is composed of three layers—a capsid that contains the viral DNA, a protein layer called the tegument and an outer envelope that is studded with viral glycoproteins (proteins with a ...