An illustration of the pain signaling pathway elicited by CGRP. CGRP activates the CGPR receptor on Schwann cells. The CGPR receptor traffics to endosomes, where sustained signaling results in the ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have increased year by year. HCC research has increasingly focused on ...