The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more ...

Structural variants in the human genome include cytogenetically detectable and submicroscopic deletions, duplications, large-scale copy-number variants, inversions and translocations. The ability ...

Analysis of individual human genomes has revealed an unexpected amount of variability in human populations. Copy number variation (CNV) has recently been identified as a major cause of structural ...

The most advanced engineering of human cell lines to date has been accomplished by scientists, demonstrating that genomes are more robust against significant structural changes than previously ...