Seizures occur in many children with Tay-Sachs disease as the condition progresses. When a child is around eight to ten ...

In 2021, he and his wife Myra experienced the devastating loss of their daughter, Havi, to Tay-Sachs disease, a rare genetic disorder that primarily affects infants and young children. Tay-Sachs ...

In one particular variant of this disease known as mucopolysaccharidosis I (MPS I), a deficiency of the enzyme alpha-L-iduronidase causes a build up of GAGs in tissues and organs, which in turn ...