Vitiligo is an autoimmune condition in which cells known as melanocytes are killed off in certain areas of the skin. Melanocytes produce melanin, a substance which gives the skin its pigmentation.

Incyte is preparing to take an oral JAK inhibitor into phase 3 trials for the skin depigmentation disease vitiligo, after reporting mid-stage data showing efficacy in patients with facial and full ...

Ellis van Creveld syndrome and Weyers acrofacial dysostosis are two rare genetic diseases affecting skeletal development. They are both ciliopathies, as they are due to malfunction of primary cilia, ...

This case-control study was conducted aiming to investigate the association between two single nucleotide polymorphisms (SNP) of CDH1 and susceptibility to develop vitiligo in a Mexican population: ...

Mice were housed in facilities approved by the Association for Assessment and Accreditation of Laboratory Animal Care International (AALAC). All animals were handled in accordance with protocols ...

1 National Human Genome Research Institute, National Institutes of Health, Bldg 49, Room 4B75, 49 Convent Drive, Bethesda, MD 20892-4472, USA 2 Department of Medical Genetics, Children’s National ...