It’s been three years since General Hospital paired Kelly Monaco’s Sam with Dominic Zamprogna’s Dante. The couple seemingly came out of nowhere after Kelly had been paired with leads Steve Burton and Billy Miller.

"She's a remarkable person. She's tough as nails and admirable in so many ways, and it’s been cool to become a friend of hers. And that won't end," Zamprogna said of Monaco

Dominic Zamprogna explained how he and Kelly Monaco got close in real life and about their last scenes together.

Kelly Monaco ended her 21-year run on General Hospital last week, and now some of her co-stars are sharing their thoughts on her departure. Monaco, who played Sam McCall on the daytime drama since 2003 and filmed more than 2,

After 20 years on the show, "General Hospital" this week is saying goodbye to Sam McCall, played by Kelly Monaco.

Since General Hospital paired Sam and Dante, their portrayers had grown closer than ever before. “You become fast friends with people that you work with like that,” Dominic Zamprogna tells Soap Opera Digest.