Topline results from a phase 2/3 clinical trial showed that an eIF2B agonist to treat ALS failed to meet its primary endpoint of slowing disease progression compared with placebo at week 24.According ...
Backed by ARCH Venture Partners, F-Prime Capital and Mubadala Capital, the new company will develop a pipeline of ...
DNL343 and fosigotifator are made to activate the ISR pathway protein eIF2B, but both failed to slow ALS progression in the HEALEY trial.
For the primary analysis, a total of 186 participants who received DNL343 treatment were compared to 139 participants who ...
A state of emergency has been declared in Russia's western city of Engels, according to the region's governor. It comes after Ukraine said it was behind a drone strike on a Russian oil base in the ...
After Donald Trump suggested he might take over Greenland by force, the consensus among the island’s population appears to be bewilderment and anxiety. By Jeffrey Gettleman and Maya Tekeli ...
Fast-growing wildfires raging in Los Angeles killed at least two people on Wednesday, destroying hundreds of buildings, scorching hillsides and prompting officials to order some 70,000 people to ...
Copyright 2025 The Associated Press. All Rights Reserved. Remote, icy and mostly pristine, Greenland plays an outsized role in the daily weather experienced by ...