Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.

Scientists have pinpointed and described unusual subtypes of fat cells that may help scientists explain why gut fat is linked ...

CellGenTech, headquartered in Chiba, Japan, is pioneering the use of a new cell type—adipocytes suitable for gene therapy—for ex vivo applications in a range of diseases caused by single-gene ...

It is a key component in the finely tuned energy homeostasis of adipocytes and disturbances to this process can cause ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity. A ...

Both guanylin and uroguanylin trigger lipolysis in human visceral adipocytes. Given the lipolytic action of the guanylin system on visceral adipocytes, the herein reported decrease of circulating ...

Ovarian cancer (OC), the most lethal gynecological malignancy, is the fifth leading cause of cancer-related death in women. Despite advances in treatment, the primary challenges in overcoming ovarian ...

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout ...

Ovarian cancer (OC), the most lethal gynecological malignancy, is the fifth leading cause of cancer-related death in women.