Duke University, led by projected top NBA draft pick Cooper Flagg, will play the University of Houston in the Final Four on Saturday, April 5.

Duke men’s basketball has reached its second Final Four in four seasons, and will take on No. 1-seed Houston to secure a spot in the championship game. The Blue Zone breaks down the matchup with an overview,

Duke takes on Houston Saturday in the Final Four. Can the Blue Devils continue their march toward history? Or can Houston pull the upset?

To this point, Duke has faced formidable challengers, but Houston is a unique opponent, and the Blue Devils will need to prepare for the Cougars on both sides of the ball to advance to the National Championship.

Houston’s basketball squad has earned a reputation of being considered arguably the toughest team in the nation. Now, with the Cougars getting ready to head to

Final Four picks, predictions, odds for Duke Blue Devils vs Houston Cougars NCAA Tournament March Madness game Saturday, April 5, 2025. Who wins game?

Final Four picks, predictions, odds explain why Houston Cougars will beat Duke Blue Devils in NCAA Tournament March Madness game Saturday, April 5.

Houston basketball is prepared for the challenge in its Final Four matchup against Duke, and it's going to be a classic showdown.

Auburn and Florida will get the Final Four started on Saturday at 6:09 ET. The Duke-Houston matchup will be roughly 30 minutes after the conclusion of game one. Both games will take place at the Alamodome in San Antonio, Texas, and they will both be airing on CBS.